SuperQuat, (S)-4-benzyl-5,5-dimethyl-oxazolidin-2-one for the asymmetric synthesis of α-substituted aldehydes

Reduction of alpha -substituted-(S)-N-acyl-4-benzyl-5,5-dimethyl-oxazolidin-2-ones with DIBAL-H in CH2Cl2 affords alpha -substituted aldehydes with no loss of stereochemical integrity at their alpha -centre. (C) 2000 Elsevier Science Ltd. All rights reserved.