Recent work(1-3) has demonstrated the self-assembly of designed periodic two-dimensional arrays composed of DNA tiles, in which the intermolecular contacts are directed by 'sticky' ends. In a mathematical context, aperiodic mosaics may be formed by the self-assembly of 'Wang' tiles(4), a process that emulates the operation of a Turing machine. Macroscopic self-assembly has been used to perform computations(5); there is also a logical equivalence between DNA sticky ends and Wang tile edges(6,7). This suggests that the self-assembly of DNA-based tiles could be used to perform DNA-based computation(8). Algorithmic aperiodic self-assembly requires greater fidelity than periodic self-assembly, because correct tiles must compete with partially correct tiles. Here we report a one-dimensional algorithmic self-assembly of DNA triple-crossover molecules(9) that can be used to execute four steps of a logical (cumulative XOR) operation on a string of binary bits.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据