The relation between mitral annulus motion and ejection fraction: A nonlinear function

In previous studies of the relation between mitral annulus motion (MAM) and left ventricular election fraction (EF), a linear relationship has been suggested. In this meta-analysis of 434 patients, we show that the relation is nonlinear and that a linear regression model overestimates EP in the lower range of MAM. The relation is better described by an S function and is influenced by age and heart size.