期刊
ANALYTICA CHIMICA ACTA
卷 891, 期 -, 页码 144-150出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.aca.2015.08.009
关键词
Conductance; Biosensor; Glucose; Hydrogen peroxide; Ag nanoparticles; Ultra-low ionic strength
资金
- National Natural Science Foundation of China [21165010, 21465014, 21465015]
- Young Scientist Foundation of Jiangxi Province [20112BCB23006, 20122BCB23011]
- Open Project Program of State Key Laboratory of Electroanalytical Chemistry [SKLEAC201310]
- Open Project Program of Key Laboratory of Functional Small Organic Molecule, Ministry of Education, Jiangxi Normal University [KLFS-KF-201410, KLFS-KF-201416]
- Innovation Foundation for Graduate Student of Jiangxi Province
- Jiangxi Normal University [YC2014-S159]
A simple, sensitive and effective method to detect glucose in ultra-low ionic strength solution containing citrate-capped silver nanoparticles (CCAgNPs) was developed by monitoring the change of solution conductance. Glucose was catalyzed into gluconic acid firstly by glucose oxidase in an O-2-saturated solution accompanied by the reduction of O-2 into hydrogen peroxide (H2O2). Then, CCAgNPs was oxidized by H2O2 into Ag+ and the capping regent of citrate was released at the same time. All these resulted Ag+, gluconic acid and the released citrate would contribute to the increase of solution ionic strength together, leading to a detectable increase of solution conductance. And a novel conductance glucose biosensor was developed with a routine linear range of 0.06-4.0 mM and a suitable detection limit of 18.0 mu M. The novel glucose biosensor was further applied in energy drink sample and proven to be suitable for practical system with low ionic strength. The proposed conductance biosensor achieved a significant breakthrough of glucose detection in ultra-low ionic strength media. (C) 2015 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据