期刊
JOURNAL OF CHEMICAL NEUROANATOMY
卷 20, 期 1, 页码 49-59出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/S0891-0618(00)00067-3
关键词
Alzheimer's disease; human brain; myeloarchitectonics; neuropathology; neuron number; stereology; striatum
Celloidin mounting (embedding without infiltration) of the human central nervous system (CNS) proved to be superior to gelatin embedding for the production of serial sections ranging in thickness from 220 to 500 mum. After gallocyanin-staining, a comprehensive neuroanatomical as well as neuropathological survey of the human brain is possible, including diagnosis of Alzheimer's disease. Details of a fractionator analysis of the total striatal neuron number are described and the possible quantitative analysis of parallel immunohistochemically stained sections is discussed. (C) 2000 Elsevier Science B.V. All rights reserved.
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