4.5 Review

Functions of α3β1 integrin

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CURRENT OPINION IN CELL BIOLOGY
卷 12, 期 5, 页码 548-553

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CURRENT BIOLOGY LTD
DOI: 10.1016/S0955-0674(00)00130-7

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alpha 3 beta 1 integrin is a laminin receptor with apparently diverse functions. In epithelial cells it acts as a receptor for the basement membrane, whereas in neuronal and possibly tumor cells it mediates migration. Interactions of alpha 3 beta 1 integrin with tetraspanin proteins may provide clues to how it transduces signals that affect cell behavior.

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