期刊
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
卷 66, 期 10, 页码 4579-4581出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.66.10.4579-4581.2000
关键词
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Antisense expression of a portion of the gene encoding the major carbon catabolite repressor CREA in Aspergillus nidulans resulted in a substantial increase in the levels of glucose-repressible enzymes, both endogenous and heterologous, in the presence of glucose. The derepression effect was approximately one-half of that achieved in a null creA mutant. Unlike results for that mutant, however, growth parameters and colony morphology in the antisense transformants were not affected.
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