期刊
INFECTION AND IMMUNITY
卷 68, 期 10, 页码 6038-6040出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.68.10.6038-6040.2000
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资金
- NIAID NIH HHS [R56 AI038991, R01 AI038991, AI-38991] Funding Source: Medline
Gamma interferon (IFN-gamma) is an important cytokine in host defense against chlamydial infection. An in vitro cell culture system was used to show that IFN-gamma inhibition of chlamydial growth, as determined by diminished recovery of infectious elementary bodies, differed markedly among chlamydial strains. These differences in sensitivity among chlamydial strains to IFN-gamma-mediated inhibition may profoundly influence the clinical outcome of infection.
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