期刊
BIOLOGICAL & PHARMACEUTICAL BULLETIN
卷 32, 期 3, 页码 509-512出版社
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/bpb.32.509
关键词
Hibiscus mutabilis 'versicolor'; allergy-preventive effect; blood flow; flavonol triglycoside; mutabiloside; hen-egg white lysozyme
Allergy-preventive activity was demonstrated for the MeOH extract (HM) of the petals of Hibiscus mutabilis L. 'versicolor' MAKINO in a continuing search for allergy-preventive substances from natural sources, using the in vivo assay method. This assay system uses monitoring of a decrease in the blood How at the tail vein of mice subjected to lien egg-white lysozyme (HEL) sensitization. By bioassay-directed fractionation, a new flavonol triglycoside, querectin 3-O-[beta-D-xylopyranosyl(1 -> 2)-alpha-L-rhamnopyranosyl(1 -> 6)]-beta-D-galactopyranoside (1: mutabiloside), was isolated, together with four known flavonols identified as quercetin 3-O-[beta-D-Xylopyranosyl(1 -> 2)]-beta-D-galactopyranoside (2) and 3-O-[beta-D-Xylopyranosyl(1 -> 2)]-beta-D-galactopyranoside (3), quercetin (4) and hyperoside (5). The structure of the new flavonol 1 was elucidated by spectroscopic methods. Among these flavonol derivatives, compounds 1 and 2 showed significant allergy-preventive effects.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据