4.7 Article

GATB: Genome Assembly & Analysis Tool Box

期刊

BIOINFORMATICS
卷 30, 期 20, 页码 2959-2961

出版社

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btu406

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资金

  1. ANR (French National Research Agency) [ANR-12-EMMA-0019-01]
  2. Agence Nationale de la Recherche (ANR) [ANR-12-EMMA-0019] Funding Source: Agence Nationale de la Recherche (ANR)

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Motivation: Efficient and fast next-generation sequencing (NGS) algorithms are essential to analyze the terabytes of data generated by the NGS machines. A serious bottleneck can be the design of such algorithms, as they require sophisticated data structures and advanced hardware implementation. Results: We propose an open-source library dedicated to genome assembly and analysis to fasten the process of developing efficient software. The library is based on a recent optimized de-Bruijn graph implementation allowing complex genomes to be processed on desktop computers using fast algorithms with low memory footprints.

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