期刊
ORGANIC LETTERS
卷 2, 期 21, 页码 3301-3303出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol006369a
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资金
- NIDA NIH HHS [DA 09789] Funding Source: Medline
[GRAPHICS] Cannabidiol 1 is the major nonpsychotropic, neutral constituent in most cannabis preparations. It is devoid of the psychoactive properties typical of cannabis; however, it produces numerous, potentially therapeutic pharmacological effects, some of which may be due to its metabolites. We report now the first total synthesis of 7-hydroxycannabidiol 2, a primary metabolite of cannabidiol, in an eight-step procedure.
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