期刊
BIOINFORMATICS
卷 30, 期 3, 页码 428-430出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btt684
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资金
- Heller Research Fellowship
- Wellcome Trust [084071]
- Royal Society Wolfson Research Merit Award [WM100023]
- IMI-JU OncoTrack [115234]
- EU-FP7 project IDEAL [259679]
- EU-FP7 project EPIGENESYS [257082]
- EU-FP7 project BLUEPRINT [282510]
The Illumina Infinium HumanMethylation450 BeadChip is a new platform for high-throughput DNA methylation analysis. Several methods for normalization and processing of these data have been published recently. Here we present an integrated analysis pipeline offering a choice of the most popular normalization methods while also introducing new methods for calling differentially methylated regions and detecting copy number aberrations.
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