期刊
BIOINFORMATICS
卷 29, 期 22, 页码 2933-2935出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btt509
关键词
-
类别
资金
- Howard Hughes Medical Institute
Infernal builds probabilistic profiles of the sequence and secondary structure of an RNA family called covariance models (CMs) from structurally annotated multiple sequence alignments given as input. Infernal uses CMs to search for new family members in sequence databases and to create potentially large multiple sequence alignments. Version 1.1 of Infernal introduces a new filter pipeline for RNA homology search based on accelerated profile hidden Markov model (HMM) methods and HMM-banded CM alignment methods. This enables similar to 100-fold acceleration over the previous version and similar to 10 000-fold acceleration over exhaustive non-filtered CM searches.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据