期刊
BIOINFORMATICS
卷 29, 期 8, 页码 1078-1080出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btt079
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资金
- National Research Foundation of Korea (NRF)
- Korean government (MEST) [2012-0001641, 2012-0009480]
A large number of proteins function as homo-oligomers; therefore, predicting homo-oligomeric structure of proteins is of primary importance for understanding protein function at the molecular level. Here, we introduce a web server for prediction of protein homo-oligomer structure. The server takes a protein monomer structure as input and predicts its homo-oligomer structure from oligomer templates selected based on sequence and tertiary/quaternary structure similarity. Using protein model structures as input, the server shows clear improvement over the best methods of CASP9 in predicting oligomeric structures from amino acid sequences.
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