期刊
BIOINFORMATICS
卷 29, 期 11, 页码 1458-1460出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btt150
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资金
- National Science Foundation [NSF: DBI 0849896, MCB 0821096, MCB 1021718]
- Direct For Biological Sciences
- Div Of Molecular and Cellular Bioscience [0821096] Funding Source: National Science Foundation
Gene duplication occurs via different modes such as segmental and single-gene duplications. Transposed gene duplication, a specific form of single-gene duplication, 'copies' a gene from an ancestral chromosomal location to a novel location. MCScanX is a toolkit for detection and evolutionary analysis of gene colinearity. We have developed MCScanX-transposed, a software package to detect transposed gene duplications that occurred within different epochs, based on execution of MCScanX within and between related genomes. MCScanX-transposed can be also used for integrative analysis of gene duplication modes for a genome and to annotate a gene family of interest with gene duplication modes.
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