期刊
BIOINFORMATICS
卷 28, 期 7, 页码 1026-1027出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bts035
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资金
- Australian Research Council [LP100100092]
- National Health and Medical Research Council (NHMRC) [APP1002898]
- Australian Research Council [LP100100092] Funding Source: Australian Research Council
Both alignment generation and visualization are important processes for producing biologically meaningful sequence alignments. Computational tools that combine reliable, automated and semi-automated approaches to produce secondary structure-based alignments with an appropriate visualization of the results are rare. We have developed SBAL, a tool to generate and edit secondary structure-based sequence alignments. It is easy to install and provides a user-friendly interface. Sequence alignments are displayed, with secondary structure assignments mapped to their corresponding regions in the sequence by using a simple colour scheme. The algorithm implemented for automated and semi-automated secondary structure-based alignment calculations shows a comparable performance to existing software.
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