4.7 Article

hmChIP: a database and web server for exploring publicly available human and mouse ChIP-seq and ChIP-chip data

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BIOINFORMATICS
卷 27, 期 10, 页码 1447-1448

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OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btr156

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  1. National Institute of Health [R01HG005220]

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hmChIP is a database of genome-wide chromatin immunoprecipitation (ChIP) data in human and mouse. Currently, the database contains 2016 samples from 492 ChIP-seq and ChIP-chip experiments, representing a total of 170 proteins and 11 069 914 protein-DNA interactions. A web server provides interface for database query. Protein-DNA binding intensities can be retrieved from individual samples for user-provided genomic regions. The retrieved intensities can be used to cluster samples and genomic regions to facilitate exploration of combinatorial patterns, cell-type dependencies, and cross-sample variability of protein-DNA interactions.

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