期刊
BIOINFORMATICS
卷 27, 期 5, 页码 720-722出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btq722
关键词
-
类别
资金
- National Institutes of Health [P40 RR024928, R01LM009722, T32 HL007910, P01 HL53586]
- Indiana Clinical and Translational Sciences Institute Bioinformatics and Advanced Information Technology Cores [U54 RR025761]
Retroviral integration has been implicated in several biomedical applications, including identification of cancer-associated genes and malignant transformation in gene therapy clinical trials. We introduce an efficient and scalable method for fast identification of viral vector integration sites from long read high-throughput sequencing. Individual sequence reads are masked to remove non-genomic sequence, aligned to the host genome and assembled into contiguous fragments used to pinpoint the position of integration.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据