4.7 Article

The Infobiotics Workbench: an integrated in silico modelling platform for Systems and Synthetic Biology

期刊

BIOINFORMATICS
卷 27, 期 23, 页码 3323-3324

出版社

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btr571

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资金

  1. EPSRC [EP/J004111/1, EP/I031642/1]
  2. BBSRC [BB/D019613/1]
  3. Juan de la Cierva fellowship [TIN2009-13192]
  4. Biotechnology and Biological Sciences Research Council [BB/D019613/1] Funding Source: researchfish
  5. BBSRC [BB/D019613/1] Funding Source: UKRI

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The Infobiotics Workbench is an integrated software suite incorporating model specification, simulation, parameter optimization and model checking for Systems and Synthetic Biology. A modular model specification allows for straightforward creation of large-scale models containing many compartments and reactions. Models are simulated either using stochastic simulation or numerical integration, and visualized in time and space. Model parameters and structure can be optimized with evolutionary algorithms, and model properties calculated using probabilistic model checking.

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