期刊
BIOINFORMATICS
卷 26, 期 17, 页码 2204-2207出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btq351
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类别
资金
- National Human Genome Research Institute [5P41HG002371-09, 5U41HG004568-02]
- Howard Hughes Medical Institute
Big Wig and Big Bed files are compressed binary indexed files containing data at several resolutions that allow the high-performance display of next-generation sequencing experiment results in the UCSC Genome Browser. The visualization is implemented using a multi-layered software approach that takes advantage of specific capabilities of web-based protocols and Linux and UNIX operating systems files, R trees and various indexing and compression tricks. As a result, only the data needed to support the current browser view is transmitted rather than the entire file, enabling fast remote access to large distributed data sets.
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