4.7 Article

RPPanalyzer: Analysis of reverse-phase protein array data

期刊

BIOINFORMATICS
卷 26, 期 17, 页码 2202-2203

出版社

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btq347

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资金

  1. German Federal Ministry of Education and Science [FKZ: 01GS0890]
  2. Project BreastSys in the platform Medical Systems Biology [FKZ: 03153968]
  3. Network IG Cellular Systems Genomics in the platform NGFNplus [FKZ: 01GS0864]
  4. Clinical Research Group 179 through the DFG

向作者/读者索取更多资源

RPPanalyzer is a statistical tool developed to read reverse-phase protein array data, to perform the basic data analysis and to visualize the resulting biological information. The R-package provides different functions to compare protein expression levels of different samples and to normalize the data. Implemented plotting functions permit a quality control by monitoring data distribution and signal validity. Finally, the data can be visualized in heatmaps, boxplots, time course plots and correlation plots. RPPanalyzer is a flexible tool and tolerates a huge variety of different experimental designs.

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