期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 44, 期 11, 页码 3203-3205出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.44.11.3203-3205.2000
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Tetracycline is an important component of combination therapies for Helicobacter pylori eradication. Twenty-nine tetracycline-resistant isolates requiring MICs ranging from 4 to 16 mug/ml were isolated from Korean (22 of 460) and Japanese (7 of 105) patients. Interestingly, all of the 29 tetracycline-resistant isolates exhibited cross-resistance to metronidazole, and the cross-resistance was transferred to tetracycline-sensitive H. pylori strains.
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