期刊
BIOINFORMATICS
卷 26, 期 15, 页码 1920-1921出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btq298
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资金
- EU [ISF 592/07, BSF 2007219]
- SCCB
- Sudarsky Center for Computational Biology
The miRror application provides insights on microRNA (miRNA) regulation. It is based on the notion of a combinatorial regulation by an ensemble of miRNAs or genes. miRror integrates predictions from a dozen of miRNA resources that are based on complementary algorithms into a unified statistical framework. For miRNAs set as input, the online tool provides a ranked list of targets, based on set of resources selected by the user, according to their significance of being coordinately regulated. Symmetrically, a set of genes can be used as input to suggest a set of miRNAs. The user can restrict the analysis for the preferred tissue or cell line. miRror is suitable for analyzing results from miRNAs profiling, proteomics and gene expression arrays.
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