期刊
BIOINFORMATICS
卷 25, 期 24, 页码 3317-3318出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btp586
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资金
- ANR (Agence Nationale de la Recherche)
The CRISPR genomic structures (Clustered Regularly Interspaced Short Palindromic Repeats) form a family of repeats that is largely present in archaea and frequent in bacteria. On the basis of a formal model of CRISPR using very few parameters, a systematic study of all their occurrences in all available genomes of Archaea and Bacteria has been carried out. This has resulted in a relational database, CRISPI, which also includes a complete repertory of associated CRISPR-associated genes (CAS). A user-friendly web interface with many graphical tools and functions allows users to extract results, find CRISPR in personal sequences or calculate sequence similarity with spacers.
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