期刊
BIOINFORMATICS
卷 25, 期 24, 页码 3323-3324出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btp577
关键词
-
类别
资金
- Max-Planck-Society
- DFG [Br1416]
- EU Commisson (MYORES network of excellence)
- Kerckhoff-Foundation
- Excellence Initiative 'Cardiopulmonary System'
The Exon Array Analyzer (EAA) is a web server, which provides a user-friendly interface to identify alternative splicing events analyzed with Affymetrix Exon Arrays. The EAA implements the Splice Index algorithm to identify differential expressed exons. The use of various filters allows reduction of the number of false positive hits. Results are presented with detailed annotation information and graphics to identify splice events and to facilitate biological validations. To demonstrate the versatility of the EAA, we analyzed exon arrays of 11 different murine tissues using sample data provided by Affymetrix (http://www.affymetrix.com). Data from the heart were compared with other tissues to identify exons that undergo heart-specific alternatively splicing, resulting in the identification of 885 differentially expressed probe sets in 649 genes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据