相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Evidence for only two independent pathways for decreasing senescence in Caenorhabditis elegans
Kelvin Yen et al.
AGE (2010)
Reversal of the glycolytic phenotype by dichloroacetate inhibits metastatic breast cancer cell growth in vitro and in vivo
Ramon C. Sun et al.
BREAST CANCER RESEARCH AND TREATMENT (2010)
Metabolic Networks of Longevity
Riekelt H. Houtkooper et al.
CELL (2010)
When a theory of aging ages badly
Jerome Lapointe et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2010)
Signaling by ROS drives inflammasome activation
Fabio Martinon
EUROPEAN JOURNAL OF IMMUNOLOGY (2010)
Establishing the Significance and Optimal Intake of Dietary Antioxidants: The Biomarker Concept
Barry Halliwell
NUTRITION REVIEWS (2010)
Mitochondrial function as a determinant of life span
Ian R. Lanza et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2010)
Caenorhabditis elegans Life Span Studies: The Challenge of Maintaining Synchronous Cohorts
Jan Gruber et al.
REJUVENATION RESEARCH (2010)
The ageing epigenome: Damaged beyond repair?
David A. Sinclair et al.
AGEING RESEARCH REVIEWS (2009)
How mitochondria produce reactive oxygen species
Michael P. Murphy
BIOCHEMICAL JOURNAL (2009)
A novel function of lipid droplets in regulating longevity
Alexander A. Goldberg et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2009)
Oxidative stress and human diseases: Origin, link, measurement, mechanisms, and biomarkers
Daniela Giustarini et al.
CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES (2009)
Can we intervene in human ageing?
Richard G. A. Faragher et al.
EXPERT REVIEWS IN MOLECULAR MEDICINE (2009)
Deceptively simple but simply deceptive - Caenorhabditis elegans lifespan studies: Considerations for aging and antioxidant effects
Jan Gruber et al.
FEBS LETTERS (2009)
Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans
Alexander A. Soukas et al.
GENES & DEVELOPMENT (2009)
Quantitative Lipid Analysis and Life Span of the fat-3 Mutant of Caenorhabditis elegans
S. Luke Hillyard et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2009)
Number matters: control of mammalian mitochondrial DNA copy number
Laura L. Clay Montier et al.
JOURNAL OF GENETICS AND GENOMICS (2009)
Can We Develop Genetically Tractable Models to Assess Healthspan (Rather Than Life Span) in Animal Models?
Marc Tatar
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2009)
Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C-elegans
Marta Artal-Sanz et al.
NATURE (2009)
Changing course in ageing research: The Healthy Ageing Phenotype
Oscar H. Franco et al.
MATURITAS (2009)
Stochastic Drift in Mitochondrial DNA Point Mutations: A Novel Perspective Ex Silico
Suresh Kumar Poovathingal et al.
PLOS COMPUTATIONAL BIOLOGY (2009)
Deletion of the Mitochondrial Superoxide Dismutase sod-2 Extends Lifespan in Caenorhabditis elegans
Jeremy M. Van Raamsdonk et al.
PLOS GENETICS (2009)
Dietary restriction by bacterial deprivation increases life span in wild-derived nematodes
George L. Sutphin et al.
EXPERIMENTAL GERONTOLOGY (2008)
The mitochondrial free radical theory of ageing - Where do we stand?
Jan Gruber et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2008)
A dynamic and chamber-specific mitochondrial remodeling in right ventricular hypertrophy can be therapeutically targeted
Jayan Nagendran et al.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2008)
Fat Metabolism Links Germline Stem Cells and Longevity in C. elegans
Meng C. Wang et al.
SCIENCE (2008)
Age-dependent kinetics and metabolism of dichloroacetate: Possible relevance to toxicity
Albert L. Shroads et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
ROS as signalling molecules:: mechanisms that generate specificity in ROS homeostasis
Benoit D'Autreaux et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Mitochondria and ageing: winning and losing in the numbers game
Joao F. Passes et al.
BIOESSAYS (2007)
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
Sebastien Bonnet et al.
CANCER CELL (2007)
Visualizing hidden heterogeneity in isogenic populations of C-elegans
DQ Wu et al.
EXPERIMENTAL GERONTOLOGY (2006)
Cells discover fire: Employing reactive oxygen species in development and consequences for aging
JP de Magalhaes et al.
EXPERIMENTAL GERONTOLOGY (2006)
Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production
A Trifunovic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Platelet mitochondrial evaluation during cytochrome c and dichloroacetate treatments of MELAS
K Nakano et al.
MITOCHONDRION (2005)
On the importance of fatty acid composition of membranes for aging
AJ Hulbert
JOURNAL OF THEORETICAL BIOLOGY (2005)
Metabolism, physiology and stress defense in three aging Ins/IGF-1 mutants of the nematode Caenorhabditis elegans
K Houthoofd et al.
AGING CELL (2005)
α-MUPA mice:: a transgenic model for longevity induced by caloric restriction
R Miskin et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2005)
The influence of genes on the aging process of mice: A statistical assessment of the genetics of aging
JP de Magalhaes et al.
GENETICS (2005)
Markers of protein oxidation: Different oxidants give rise to variable yields of bound and released carbonyl products
HA Headlam et al.
FREE RADICAL BIOLOGY AND MEDICINE (2004)
Measuring reactive species and oxidative damage in vivo and in cell culture:: how should you do it and what do the results mean?
B Halliwell et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
Mitochondrial complex I mutations in Caenorhabditis elegans produce cytochrome c oxidase deficiency, oxidative stress and vitamin-responsive lactic acidosis
LI Grad et al.
HUMAN MOLECULAR GENETICS (2004)
Aging in a very short-lived nematode
MP Gardner et al.
EXPERIMENTAL GERONTOLOGY (2004)
Mitochondrial formation of reactive oxygen species
JF Turrens
JOURNAL OF PHYSIOLOGY-LONDON (2003)
Stochastic and genetic factors influence tissue-specific decline in ageing C-elegans
LA Herndon et al.
NATURE (2002)
Mechanisms of aging: An appraisal of the oxidative stress hypothesis
RS Sohal et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
The evolution of mammalian aging
JP de Magalhaes et al.
EXPERIMENTAL GERONTOLOGY (2002)
Insulin/IGF signalling and ageing: seeing the bigger picture
D Gems et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2001)
Why do life spans differ? Partitioning mean longevity differences in terms of age-specific mortality parameters
SD Pletcher et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2000)