期刊
TRENDS IN BIOCHEMICAL SCIENCES
卷 25, 期 11, 页码 555-560出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/S0968-0004(00)01688-1
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资金
- NINDS NIH HHS [NS39854, NS28828, NS11766] Funding Source: Medline
Mitochondrial respiratory chain diseases are a highly diverse group of disorders whose main unifying characteristic is the impairment of mitochondrial function. As befits an organelle containing gene products encoded by both mitochondrial DNA (mtDNA) and nuclear DNA (nDNA), these diseases can be caused by inherited errors in either genome, but a surprising number are sporadic, and a few are even caused by environmental factors.
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