期刊
DRUG NEWS & PERSPECTIVES
卷 13, 期 9, 页码 517-522出版社
PROUS SCIENCE, SAU-THOMSON REUTERS
DOI: 10.1358/dnp.2000.13.9.858479
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The ability of heat shock proteins to chaperone peptides, including antigenic peptides; to interact with antigen-presenting cells through a receptor; to stimulate antigen-presenting cells to secrete inflammatory cytokines; and to mediate maturation of dendritic cells makes them a unique starting point for generation of immune responses. These properties also permit the utilization of heat shock proteins for development of a new generation of prophylactic and therapeutic vaccines against cancers and infectious diseases. (C) 2000 Prous Science. All rights reserved.
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