期刊
MICROBES AND INFECTION
卷 2, 期 14, 页码 1743-1756出版社
EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/S1286-4579(00)01329-0
关键词
interferon; hepatitis C virus; protein kinase; PKR
Interferon plays a critical role in the host's natural defense against viral infections and in their treatment. It is the only therapy for hepatitis C virus (HCV) infection; however, many virus isolates are resistant. Several HCV proteins have been shown to possess properties that enable the virus to evade the interferon-mediated cellular antiviral responses. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
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