期刊
BIOFOULING
卷 25, 期 5, 页码 413-427出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/08927010902853516
关键词
quorum sensing; inhibitors; biofouling; biofilm formation; marine environment; Gram-negative bacteria
资金
- Smithsonian Institution (USA)
- SQU [IG/AGR/FISH/09/03]
- Florida Sea [NA060AR4170014 R/LR-MB-27]
- CRIS [FLA-SWS-04591]
- National Oceanic and Atmospheric Administration [NA05NOS4781194]
- NOAA
- US Department of Commerce [NA06OAR4170014]
Bacterial quorum sensing (QS) is a cell-cell communication and gene regulatory mechanism that allows bacteria to coordinate swarming, biofilm formation, stress resistance, and production of toxins and secondary metabolites in response to threshold concentrations of QS signals that accumulate within a diffusion-limited environment. This review focuses on the role of QS signaling and QS inhibition in marine bacteria by compounds derived from marine organisms. Since the formation of a biofilm is considered to be an initial step in the development of fouling, direct and indirect effects of QS signals and inhibitors on the process of marine biofouling are discussed. Directions for future investigations and QS-related biotechnological applications are highlighted.
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