New terpenoids from a Cacospongia sp from the Philippines

Four new terpenoids, cacospongins A (1), B (2), C (3) and D (4), have been isolated from the Philippine sponge Cacospongia sp. Also isolated were 15,16-epoxy-8(17),13(16),14-labdatriene (5), ambliofuran (6) and luffariellolide (7). The structures of compounds 1-7 were determined by means of spectroscopic evidence. (C) 2000 Elsevier Science Ltd. All rights reserved.