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Daniel H. Lackner et al.
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Lynda M. Groocock et al.
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Dephosphorylation Enables the Recruitment of 53BP1 to Double-Strand DNA Breaks
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Alexandre Orthwein et al.
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Cristina Bartocci et al.
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Elsa Callen et al.
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Sabrina L. Spencer et al.
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Anthony J. Cesare et al.
MOLECULAR CELL (2013)
RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection
J. Ross Chapman et al.
MOLECULAR CELL (2013)
A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice
Cristina Escribano-Diaz et al.
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Regulation of DNA Damage Responses by Ubiquitin and SUMO
Stephen P. Jackson et al.
MOLECULAR CELL (2013)
A two-step mechanism for TRF2-mediated chromosome-end protection
Keiji Okamoto et al.
NATURE (2013)
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark
Amelie Fradet-Turcotte et al.
NATURE (2013)
Push back to respond better: regulatory inhibition of the DNA double-strand break response
Stephanie Panier et al.
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Michal Zimmermann et al.
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Rif1 Prevents Resection of DNA Breaks and Promotes Immunoglobulin Class Switching
Michela Di Virgilio et al.
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RTEL1 Dismantles T Loops and Counteracts Telomeric G4-DNA to Maintain Telomere Integrity
Jean-Baptiste Vannier et al.
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RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling
Francesca Mattiroli et al.
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Anthony J. Cesare et al.
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Zeenia Kaul et al.
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Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation
Marzia Fumagalli et al.
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A telomere-dependent DNA damage checkpoint induced by prolonged mitotic arrest
Makoto T. Hayashi et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Removal of Shelterin Reveals the Telomere End-Protection Problem
Agnel Sfeir et al.
SCIENCE (2012)
Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
Graeme Hewitt et al.
NATURE COMMUNICATIONS (2012)
Give me a break, but not in mitosis The mitotic DNA damage response marks DNA double strand breaks with early signaling events
Simona Giunta et al.
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Quantitative Phospho-proteomics to Investigate the Polo-like Kinase 1-Dependent Phospho-proteome
Karin Grosstessner-Hain et al.
MOLECULAR & CELLULAR PROTEOMICS (2011)
DNA-damage response and repair activities at uncapped telomeres depend on RNF8
Marieke H. Peuscher et al.
NATURE CELL BIOLOGY (2011)
More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance
Jiri Lukas et al.
NATURE CELL BIOLOGY (2011)
SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair
Yung C. Lam et al.
EMBO JOURNAL (2010)
DNA damage signaling in response to double-strand breaks during mitosis
Simona Giunta et al.
JOURNAL OF CELL BIOLOGY (2010)
A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint
Marcel A. T. M. van Vugt et al.
PLOS BIOLOGY (2010)
RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins
Carsten Doil et al.
CELL (2009)
The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage
Grant S. Stewart et al.
CELL (2009)
DNA damage foci in mitosis are devoid of 53BP1
Glyn Nelson et al.
CELL CYCLE (2009)
The Mre11 Complex and the Response to Dysfunctional Telomeres
Claire L. Attwooll et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Cell Cycle-Dependent Role of MRN at Dysfunctional Telomeres: ATM Signaling-Dependent Induction of Nonhomologous End Joining (NHEJ) in G1 and Resection-Mediated Inhibition of NHEJ in G2
Nadya Dimitrova et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Multiple roles for MRE11 at uncapped telomeres
Yibin Deng et al.
NATURE (2009)
The DNA-damage response in human biology and disease
Stephen P. Jackson et al.
NATURE (2009)
Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions
Anthony J. Cesare et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility
Nadya Dimitrova et al.
NATURE (2008)
A quantitative atlas of mitotic phosphorylation
Noah Dephoure et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence
Asako J Nakamura et al.
Epigenetics & Chromatin (2008)
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
Nadine K. Kolas et al.
SCIENCE (2007)
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly
Michael S. Y. Huen et al.
CELL (2007)
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
Niels Mailand et al.
CELL (2007)
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1
Eros Lazzerini Denchi et al.
NATURE (2007)
Spreading of mammalian DNA-damage response factors studied by ChIP-chip at damaged telomeres
Andreas Meier et al.
EMBO JOURNAL (2007)
MDC1 accelerates nonhomologous end-joining of dysfunctional telomeres
Nadya Dimitrova et al.
GENES & DEVELOPMENT (2006)
The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres
Ramiro E. Verdun et al.
CELL (2006)
Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination
Giulia B. Celli et al.
NATURE CELL BIOLOGY (2006)
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
M Stucki et al.
CELL (2005)
Functional human telomeres are recognized as DNA damage in G2 of the cell cycle
RE Verdun et al.
MOLECULAR CELL (2005)
DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion
GB Celli et al.
NATURE CELL BIOLOGY (2005)
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
JH Lee et al.
SCIENCE (2005)
Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex
JH Lee et al.
SCIENCE (2004)
Inhibition of DNA decatenation, but not DNA damage, arrests cells at metaphase
DA Skoufias et al.
MOLECULAR CELL (2004)
DNA damage foci at dysfunctional telomeres
H Takai et al.
CURRENT BIOLOGY (2003)
DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint
A Mikhailov et al.
CURRENT BIOLOGY (2002)
DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2
A Smogorzewska et al.
CURRENT BIOLOGY (2002)
ATM phosphorylates histone H2AX in response to DNA double-strand breaks
S Burma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
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