期刊
BIOESSAYS
卷 35, 期 8, 页码 706-716出版社
WILEY
DOI: 10.1002/bies.201300028
关键词
cooperation; host range; microbial ecology; social evolution; toxin; virulence
资金
- NERC
- BBSRC
- Royal Society
- NERC [NE/E012671/2] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/C512702/1] Funding Source: researchfish
- Natural Environment Research Council [NE/E012671/2] Funding Source: researchfish
How significant is social evolution theory for the maintenance of virulence in natural populations? We assume that secreted, distantly acting virulence factors are highly likely to be cooperative public goods. Using this assumption, we discuss and critically assess the potential importance of social interactions for understanding the evolution, diversity and distribution of virulence in the Bacillus cereus group, a novel study system for microbial social biology. We conclude that dynamic equilibria in Cry toxin production, as well as strong spatial structure and population bottlenecks in hosts are the main ecological factors maintaining the cooperative secretion of virulence factors and argue that collective action has contributed to the evolution of narrow host range. Non-linearities in the benefits associated with public goods, as well as the lack of private secretion systems in the Firmicutes may also explain the prevalence and importance of distantly acting virulence factors in B. cereus and its relatives.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据