Fluorine containing β-cyclodextrin:: a new class of amphiphilic carriers

beta -cyclodextrins (beta -CD), functionalised at the 6-position with trifluoromethylthio groups, are obtained in five steps from the native beta -CD The fluorinated cyclodextrin derivatives exhibit an amphiphilic behaviour at the air water interface and thus are good candidates for a new class of amphiphilic carriers. (C) 2000 Elsevier Science Ltd. All rights reserved.