Unique selectivity of iodohydroxylation reaction of allenyl phenyl sulfoxides in aqueous MeCN.: A stereodefined synthesis of (E)-2-iodo-3-hydroxy-1-alkenyl sulfoxides

Iodohydroxylation reaction of allenyl phenyl sulfoxides with I-2 can smoothly proceed to generate (E)-2-iodo-3-hydroxy-1-alkenyl sulfoxides with excellent regio- and stereoselectivity in high or excellent yields. The configuration of E-2a was determined by the X-ray diffraction study.