期刊
BIOESSAYS
卷 32, 期 12, 页码 1040-1049出版社
WILEY-BLACKWELL
DOI: 10.1002/bies.201000083
关键词
cell division; checkpoint; mitochondria; organelle inheritance; Saccharomyces cerevisiae
资金
- NIH [GM45735]
Movement and positional control of mitochondria and other organelles are coordinated with cell cycle progression in the budding yeast, Saccharomyces cerevisiae. Recent studies have revealed a checkpoint that inhibits cytokinesis when there are severe defects in mitochondrial inheritance. An established checkpoint signaling pathway, the mitotic exit network (MEN), participates in this process. Here, we describe mitochondrial motility during inheritance in budding yeast, emerging evidence for mitochondrial quality control during inheritance, and organelle inheritance checkpoints for mitochondria and other organelles.
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