期刊
BIOELECTROMAGNETICS
卷 31, 期 7, 页码 528-534出版社
WILEY
DOI: 10.1002/bem.20589
关键词
RF exposure; 848.5 MHz; rat spermatogenesis
资金
- Korea Communications Commission (KCC)
- Korea Evaluation Institute of Industrial Technology (KEIT) [KI001756] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
We examined the histological changes by radiofrequency (RF) fields on rat testis, specifically with respect to sensitive processes such as spermatogenesis. Male rats were exposed to 848.5 MHz RF for 12 weeks. The RF exposure schedule consisted of two 45-min RF exposure periods, separated by a 15-min interval. The whole-body average specific absorption rate (SAR) of RF was 2.0 W/kg. We then investigated correlates of testicular function such as sperm counts in the cauda epididymis, malondialdehyde concentrations in the testes and epididymis, frequency of spermatogenesis stages, germ cell counts, and appearance of apoptotic cells in the testes. We also performed p53, bcl-2, caspase 3, p21, and PARP immunoblotting of the testes in sham-and RF-exposed animals. Based on these results, we concluded that subchronic exposure to 848.5 MHz with 2.0 W/kg SAR RF did not have any observable adverse effects on rat spermatogenesis. Bioelectromagnetics 31: 528-534, 2010. (C) 2010 Wiley-Liss, Inc.
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