期刊
CONTROLLED CLINICAL TRIALS
卷 21, 期 6, 页码 552-560出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/S0197-2456(00)00104-5
关键词
sample size; proportional hazards regression; nonbinary covariates; variance inflation factor
This paper derives a formula to calculate the number of deaths required for a proportional hazards regression model with a nonbinary covariate. The method does not require assumptions about the distributions of survival time and predictor variables other than proportional hazards. Simulations show that the censored observations do not contribute to the power of the test in the proportional hazards model, a fact that is well known for a binary covariate. This paper also provides a variance inflation factor together with simulations for adjustment of sample size when additional covariates are included in the model. (C) Elsevier Science Inc. 2000.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据