期刊
BIOELECTROCHEMISTRY
卷 85, 期 -, 页码 36-43出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.bioelechem.2011.11.008
关键词
Fibroin-polypyrrole meshes; Electroactivity; Anion storage; Human fibroblast; Adult human mesenchymal stem cells
资金
- Spanish Government (MCI) [MAT2008-06702]
- Seneca Foundation [08684/PI/08]
- FEDER of the Region of Murcia from the UE
- INIA (Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria), Government of Spain
Scaffolds constituted by micro and nanofibers of silk fibroin were obtained by electrospinning. Fibers of fibroin meshes were coated with polypyrrole (pPy) by chemical polymerization; chemical linkages between polymers were observed by SEM and IR spectroscopy. Mechanical resistance of the meshes was improved by polypyrrole coating. Furthermore, coated meshes present a high electroactivity allowing anion storage and delivery during oxidation/reduction reactions in aqueous solutions. Uncoated and pPy coated materials support the adherence and proliferation of adult human mesenchymal stem cells (ahMSCs) or human fibroblasts (hFb). The bioactivity of fibroin mesh overcomes that of the polypyrrole coated meshes. (C) 2011 Elsevier BM. All rights reserved.
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