期刊
JOURNAL OF BIOTECHNOLOGY
卷 214, 期 -, 页码 117-118出版社
ELSEVIER
DOI: 10.1016/j.jbiotec.2015.09.020
关键词
Streptomyces ambofaciens; Genome sequence; Gene clusters; Genome instability
资金
- French National Research Agency through the Laboratory of Excellence ARBRE [ANR-11-LABX-0002-01]
- French National Research Agency [ANR StreptofluxANR-07-BLAN-0096, ANR MiGenIsANR-13-BSV6-0009]
- French National Institute for Agricultural Research (INRA)
- Region Lorraine
Streptomyces ambofaciens ATCC23877 is a soil bacterium industrially exploited for the production of the macrolide spiramycin which is used in human medicine as an antibacterial and anti-toxoplasmosis chemical. Its genome consists of a 8.3 Mbp linear chromosome and a 89 kb circular plasmid. The complete genome sequence reported here will enable us to investigate Streptomyces genome evolution and to discover new secondary metabolites with potential applications notably in human medicine. (C) 2015 Elsevier B.V. All rights reserved.
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