期刊
NATURE REVIEWS MOLECULAR CELL BIOLOGY
卷 1, 期 3, 页码 179-186出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/35043058
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As its name suggests, the ATM - 'ataxia-telangiectasia, mutated' - gene is responsible for the rare disorder ataxia-telangiectasia. Patients show various abnormalities, mainly in their responses to DNA damage, but also in other cellular processes. Although it is hard to understand how a single gene product is involved in so many physiological processes, a clear picture is starting to emerge.
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