4.4 Article

Metabolism of acyl-homoserine lactone quorum-sensing signals by Variovorax paradoxus

期刊

JOURNAL OF BACTERIOLOGY
卷 182, 期 24, 页码 6921-6926

出版社

AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.182.24.6921-6926.2000

关键词

-

资金

  1. NIAID NIH HHS [T32-AI07343, T32 AI007343] Funding Source: Medline
  2. NIGMS NIH HHS [GM59026, R01 GM059026] Funding Source: Medline

向作者/读者索取更多资源

Acyl-homoserine lactones (acyl-HSLs) serve as dedicated cell-to-cell signaling molecules in many species of the class Proteobacteria. We have addressed the question of whether these compounds can be degraded biologically. A motile, rod-shaped bacterium was isolated from soil based upon its ability to utilize N-(3-oxohexanoyl)-L-homoserine lactone as the sole source of energy and nitrogen. The bacterium was classified as a strain of Variovorax paradoxus, The V, paradoxus isolate was capable of growth on all of the acyl-HSLs tested. The molar growth yields correlated with the length of the acyl group. HSL, a product of acyl-HSL metabolism, was used as a nitrogen source, but not as an energy source. Cleavage and partial mineralization of the HSL ring were demonstrated by using radiolabeled substrate, This study indicates that some strains of V. paradoxus degrade and grow on acyl-HSL signals as the sole energy and nitrogen sources. This study provides dues about the metabolic pathway of acyl-HSL degradation by V. paradoxus.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.4
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据