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Life's 24-hour clock: molecular control of circadian rhythms in animal cells

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TRENDS IN BIOCHEMICAL SCIENCES
卷 25, 期 12, 页码 601-606

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ELSEVIER SCIENCE LONDON
DOI: 10.1016/S0968-0004(00)01695-9

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Our sleep-wake cycles and many other similar to 24-hour rhythms of behavior and physiology persist in the absence of environmental cues. Genetic and biochemical studies have shown that such rhythms are controlled by internal molecular clocks. These are assembled from the cycling RNA and protein products of a small group of genes that are conserved throughout the animal kingdom.

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