期刊
ANALYST
卷 140, 期 7, 页码 2330-2335出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4an02365j
关键词
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资金
- National Center of Science [PRELUDIUM DEC-2012/05/N/ST4/00218]
- European Union from the resources of the European Regional Development Fund under the Innovative Economy Programme [POIG.01.01.02-00-069/09]
- Engineering and Physical Sciences Research Council [1269769] Funding Source: researchfish
Intracellular redox potential is a highly regulated cellular characteristic and is critically involved in maintaining cellular health and function. The dysregulation of redox potential can result in the initiation and progression of numerous diseases. Redox potential is determined by the balance of oxidants and reductants in the cell and also by pH. For this reason a technique for quantitative measurement of intracellular redox potential and pH is highly desirable. In this paper we demonstrate how surface enhanced Raman scattering (SERS) nanosensors can be used for multiplexed measurement of both pH and redox potential in live single cells.
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