期刊
FEBS LETTERS
卷 486, 期 2, 页码 167-172出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/S0014-5793(00)02269-9
关键词
ultraviolet visual pigment; opsin; absorption spectrum; molecular evolution; vertebrate
资金
- NIGMS NIH HHS [GM42379] Funding Source: Medline
Various vertebrates use ultraviolet (UV) vision for such basic behaviors as mating, foraging, and predation. We have successfully interchanged the color-sensitivities of the mouse UV pigment and the human blue pigment by introducing forward and reverse mutations at five sites. This unveils for the first time the general mechanism of UV vision. Most contemporary UV pigments in vertebrates have maintained their ancestral functions by accumulating no more than one of the five specific amino acid changes. The avian lineage is an exception, where the ancestral pigment lost UV-sensitivity but some descendants regained it by one amino acid replacement at an entirely different site. (C) 2000 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据