4.4 Article

Novel synthesis of 3-oxazolines

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TETRAHEDRON LETTERS
卷 41, 期 50, 页码 9787-9790

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PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(00)01723-8

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3-oxazolines; 1,3-oxazolidines; N-chlorination; oxidation; 2,5-dihydrooxazoles; sodium hypochlorite

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A series of new aliphatic 3-oxazolines was obtained in moderate to good yields via oxidation of the corresponding 1,3-oxazolidines by N-chlorination with sodium hypochlorite followed by elimination in basic medium. Some of the 3-oxazolines obtained present interesting properties in the field of fragrance chemistry. (C) 2000 Elsevier Science Ltd. All rights reserved.

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