期刊
BIOCONJUGATE CHEMISTRY
卷 20, 期 1, 页码 5-14出版社
AMER CHEMICAL SOC
DOI: 10.1021/bc800278e
关键词
-
类别
资金
- Ministry of Health and Welfare
- Ministry of Education, and Science and Technology, Republic of Korea
Small interfering RNA (siRNA) has been chemically conjugated to a variety of bioactive molecules, lipids, polymers, peptides, and inorganic nanostructured materials to enhance their pharmacokinetic behavior, cellular uptake, target specificity, and safety. To efficiently deliver siRNAs to the target cells and tissues, many different siRNA bioconjugates were synthesized and characterized, and their gene silencing efficiencies were tested in vitro and in vivo. In this review, recent developments of siRNA bioconjugates are summarized.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据