期刊
BIOCONJUGATE CHEMISTRY
卷 20, 期 5, 页码 1054-1057出版社
AMER CHEMICAL SOC
DOI: 10.1021/bc900016x
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- Daicel Chemical Industries, Ltd. (Osaka, Japan)
Hyperbranched poly(glycidol)s with varying degrees of polymerization were modified by reaction with succinic anhydride and isopropylamine to obtain novel pH- and thermosensitive polymers. These polymers exhibited phase transitions in response to decreasing pH and/or increasing temperature, depending on the degree of polymerization and the ratio of succinyl group to N-isopropylamide. It was possible to harvest a bioactive molecule, rose bengal, from solution using the phase transition of thermosensitive hyperbranched poly(glycidol).
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