期刊
FEBS LETTERS
卷 487, 期 1, 页码 3-12出版社
WILEY-BLACKWELL
DOI: 10.1016/S0014-5793(00)02272-9
关键词
random sequencing; phylogenetics; bioinformatics; comparative genomics; Saccharomyces cerevisiae
The identification of molecular evolutionary mechanisms in eukaryotes is approached by a comparative genomics study of a homogeneous group of species classified as Hemiascomycetes, This group includes Saccharomyces cerevisiae the first eukaryotic genome entirely sequenced, back in 1996, A random sequencing analysis has been performed on 13 different species sharing a small genome size and a low frequency of introns, Detailed information is provided in the 20 following papers. Additional tables available on websites describe the ca, 20 000 newly identified genes. This wealth of data, so far unique among eukaryotes, allowed us to examine the conservation of chromosome maps, to identify the 'yeast-specific' genes, and to review the distribution of gene families into functional classes. This project conducted by a network of se, en French laboratories has been designated 'Genolevures'. (C) 2000 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.
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