Synthesis of a novel thiazole based dipeptide chemosensor for Cu(II) in water

A thiazole-based novel dipeptide module has been synthesized, which exhibited selective Cu(II) recognition in water in the presence of other competing divalent transition metal ions at micromolar concentrations. This is the first example of an entirely synthetic peptide based chemosensor for Cu(II). (C) 2000 Elsevier Science Ltd. All rights reserved.